Smoking a single cigarette can have immediate and long-term negative effects on your health. The inhalation of toxic chemicals in cigarette smoke can lead to immediate effects such as increased heart rate, reduced blood flow, and constriction of blood vessels. Over time, smoking can cause serious health problems such as lung cancer, heart disease, and respiratory issues. Nicotine addiction can also lead to withdrawal symptoms when attempting to quit smoking, making it difficult to break the habit. Overall, smoking even one cigarette can have a detrimental impact on your health and well-being. It is important to be aware of the risks associated with smoking and to seek help in quitting if needed.